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Publications before 2015

  • 2014
Melnyk, O.; Ollivier, N.; Besret, S.; Melnyk, P. Phenylthiocarbamate or N -carbothiophenyl group chemistry in peptide synthesis and bioconjugation. Bioconjugate Chem. 2014, 25, 629-639
Melnyk, O.; Agouridas, V. From protein total synthesis to peptide transamidation and metathesis: playing with the reversibility of N,S-acyl or N,Se-acyl migration reactions. Curr. Opin. Chem. Biol. 2014, 22, 137-145
Ollivier, N.; Blanpain, A.; Boll, E.; Raibaut, L.; Drobecq, H.; Melnyk, O. Selenopeptide transamidation and metathesis. Org. Lett. 2014, 16, 4032-4035
Besret, S.; Vicogne, J.; Dahmani, F.; Fafeur, V.; Desmet, R.; Drobecq, H.; Romieu, A.; Melnyk, P.; Melnyk, O. Thiocarbamate-linked polysulfonate-peptide conjugates as selective hepatocyte growth factor receptor binders. Bioconjugate Chem. 2014, 25, 1000-1010
Boll, E.; Drobecq, H.; Ollivier, N.; Raibaut, L.; Desmet, R.; Vicogne, J.; Melnyk, O. A novel PEG-based solid support enables the synthesis of >50 amino-acid peptide thioesters and the total synthesis of a functional SUMO-1 peptide conjugate. Chem. Sci. 2014, 5, 2017-2022
Ollivier, N.; Raibaut, L.; Blanpain, A.; Desmet, R.; Dheur, J.; Mhidia, R.; Boll, E.; Drobecq, H.; Pira, S.L.; Melnyk, O. Tidbits for the synthesis of bis(2-sulfanylethyl)amido (SEA) polystyrene resin, SEA peptides and peptide thioesters. J. Pept. Sci. 2014, 20, 92-97
Pike, S. J.; Diemer, V.; Raftery, J.; Webb, S. J.; Clayden, J. Designing Foldamer-Foldamer Interactions in Solution: The Roles of Helix Length and Terminus Functionality in Promoting the Self-Association of Aminoisobutyric Acid Oligomers. Chemistry 2014, 20, 15981-15990.
Chaumeil, H.; Neuburger, M.; Jacques, P.; Tschamber, T.; Diemer, V.; Carré, C. Conformational analysis of some pyridinium phenolates and synthetic precursors based on X-ray and IR characterisations. Tetrahedron 2014, 70, 3116-3122.
  • 2013
El-Mahdi, O.; Melnyk, O. α-oxo aldehyde or glyoxylyl group chemistry in peptide bioconjugation. Bioconjugate Chem. 2013, 24, 735-765
Raibaut, L.; Seeberger, P.; Melnyk, O. Bis(2-sulfanylethyl)amido peptides enable native chemical ligation at proline and minimize deletion side-product formation. Org. Lett. 2013, 15, 5516-5519
Pira, S. L.; Boll, E.; Melnyk, O. Synthesis of peptide thioacids at neutral pH using bis(2-sulfanylethyl) amido peptide precursors. Org. Lett. 2013, 15, 5346-5349
Raibaut, L.; Adihou, H.; Adihou, R.; Delmas, A. F.; Aucagne, V.; Melnyk, O. Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments. Chem. Sci. 2013, 4, 4061-4066
Fécourt, F.; Delpech, B.; Melnyk, O.; Crich, D. Se -(9-fluorenylmethyl) selenoesters : Preparation, reactivity, and use as convenient synthons for selenoacids. Org. Lett. 2013, 15, 3758-3761
Raibaut, L.; Vicogne, J.; Leclercq, B.; Drobecq, H.; Desmet, R.; Melnyk, O. Total synthesis of biotinylated N domain of human hepatocyte growth factor. Bioorg. Med. Chem. 2013, 21, 3486-3494
Mhidia, R.; Boll, E.; Fécourt, F.; Ermolenko, M.; Ollivier, N.; Sasaki, K.; Crich, D.; Delpech, B.; Melnyk, O. Exploration of an imide capture/N,N-acyl shift sequence for asparagine native peptide bond formation. Bioorg. Med. Chem. 2013, 21, 3479-3485
Greene, A. E.; Agouridas, V.; Deniau, E. Cesium carbonate mediated aryl trflate esters’ deprotection. Tetrahedron Lett. 2013, 54, 7078-7079
Vanderstraete, M.; Gouignard, N.; Ahier, A.; Morel, M.; Vicogne, J.; Dissous, C. The venus kinase receptor (VKR) family: Structure and evolution. BMC Genomics 2013, 14, 361
Brown, R. A.; Diemer, V.; Webb, S. J.; Clayden, J. End-to-end conformational communication through a synthetic purinergic receptor by ligand-induced helicity switching. Nat. Chem. 2013, 5, 853-860.