publications
An Iron-Catalyzed Protein Desulfurization Method Reminiscent of Aquatic Chemistry
Desmet, R.; Boidin-Wichlacz, C.; Mhidia, R.; Tasiemski, A.; Agouridas, O.; Melnyk, O. Angew. Chem. Int. Ed. 2023, 62, e202302648.
The diversification of the antimicrobial peptides from marine worms is driven by environmental conditions
Bruno, R.; Boidin-Wichlacz, C.; Melnyk, O.; Zeppilli, D.; Landon, C.; Thomas, F.; Cambon, M.-A.; Lafond, M.; Mabrouk, K.; Massol, F.; Hourdez, S.; Maresca, M.; Jollivet, D.; Tasiemski, A. STOTEN 2023, 879, 162875.
DOI: 10.1016/j.scitotenv.2023.162875
Electrostatic Assistance of 4-Mercaptophenylacetic acid catalyzed Native Chemical Ligation
Ollivier, N. ; Roy, E. ; Desmet, R. ; Agouridas, V.; Diemer, V.;Melnyk, O. Org. Lett. 2023, 25, 2696-2700.
DOI : 10.1021/acs.orglett.3c00796
Incorporation of a highly reactive oxalyl thioester-based interacting handle into proteins
Grain, B.; Desmet, R.; Snella, B.; Melnyk, O.; Agouridas, V. Org. Lett. 2023, 25, 5117-5122.
DOI: 10.1021/acs.orglett.3c01846
Pedal to the Metal: The Homogeneous Catalysis of the Native Chemical Ligation Reaction
Diemer, V.; Firstova, O.; Agouridas, V.; Melnyk, O. Chemistry 2022, 28, e202281662.
Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist
de Nola, G. ; Leclercq, B. ; Mougel, A. ;Taront, S. ;Simonneau, C. ;Forneris, F. ;Adriaenssens, E. ;Drobecq, H. ;Iamele, L. ;Dubuquoy, L.;Melnyk, O.; Gherardi, E.; de Jonge, H.;Vicogne, J. Life Sci. Alliance, 2022, 12, e202201424.
Thiol Catalysis of Selenosulfide Bond Cleavage by a Triarylphosphine
Firstova, O.; Melnyk, O.; Diemer, V. J. Org. Chem. 2022, 87, 9426–9430.
Fast Protein Modification in the Nanomolar Concentration Range Using an Oxalyl Amide as Latent Thioester
Snella, B. ; Grain, B. ; Vicogne, J ; Capet, F.; Wiltschi, B.; Melnyk, O.*; Agouridas, V.* Angew. Chem. Int. Ed. 2022, e202204992.
Redox-Controlled Chemical Protein Synthesis: Sundry Shades of Latency
Agouridas, V. ; Ollivier, N. ; Vicogne, J. ; Diemer, V.; Melnyk, O. Acc. Chem. Res. 2022, 55, 2685-2697.
DOI: 10.1021/acs.accounts.2c00436
Preview article. Protein Desulfurization: Sodium Tetraethylborate Makes It Fast
Diemer, V.; Melnyk, O. Chem 2022, 8, 2571-2573.
DOI: 10.1016/j.chempr.2022.09.011
A biomimetic electrostatic catalysis approach for guiding and promoting N-terminal protein chemical modification
Ollivier, N ; Sénéchal, M.; Desmet, R.; Snella, B.; Agouridas, V.; Melnyk, O. Nat. Commun. 2022, 13, N° 6667.
DOI: 10.1038/s41467-022-34392-5
A novel agonist for the HGF receptor MET promotes differentiation of human pluripotent stem cells into hepatocyte-like cells
Tauran, Y. ; Lereau-Bernier, M. ; Segard, B. D. ; Danoy, M. ; Kimura, K. ; Shinohara, M. ; Brioude, A. ; Sakai, Y. ; de Jonge, H. ; Melnyk, O. ; Vicogne, J. ; Leclerc, E. Dev Growth Differ. 2022, 64, 527-536.
DOI: 10.1111/dgd.12818
A Self-Purifying Microfluidic System for Identifying Drugs Acting Against Adult Schistosomes”
Girod, V. ; Ghoris, M.-J. ; Caby, S. ; Melnyk, O. ; Dissous, C. ; Senez, V. ; Vicogne, V.
Royal Society Open Science 2022, 9, N° 220648.
DOI: 10.1098/rsos.220648
Insights into the Mechanism and Catalysis of Peptide Thioester Synthesis by Alkylselenols Provide a New Tool for Chemical Protein Synthesis
Kerdraon, F.; Bogard, G.; Snella, B.; Drobecq, H.; Pichavant, M.; Agouridas, V.; Melnyk, O. Molecules 2021, 26, 1386.
DOI: 10.3390/molecules26051386
Strategies and open questions in solid phase protein chemical synthesis
Agouridas, V.; Diemer, V.; Melnyk, O. Curr. Opin. Chem. Biol. 2020, 58, 1-9.
DOI: 10.1016/j.cbpa.2020.02.007
Natural T cell epitope containing methyl-lysines on mycobacterial heparin-binding hemagglutinin
Corbière, V. ; Segers, J. ; Desmet, R. ; Lecher, S. ; Loyens, M. ; Petit, E. ; Melnyk, O. ; Locht, C. ; Mascart, F.
J. immunol. 2020, 1901214.
DOI : 10.4049/jimmunol.1901214
A cysteine selenosulfide redox switch for protein chemical synthesis
Diemer, V. ; Ollivier, N. ; Leclercq, B. ; Drobecq, H. ; Vicogne, J. ; Agouridas, V. ; Melnyk, O.
Nat. Commun., 2020, 11, 2558.
DOI : 10.1038/s41467-020-16359-6
Comment on « N-terminal Protein Tail Acts as Aggregation Protective Entropic Bristles : The SUMO Case
Sénéchal, M. ; Bouchenna, J. ; Vicogne, V. ; Melnyk, O. Biomacromolecules, 2020, 8, 3480-3482.
DOI : 10.1021/acs.biomac.0c00185
Catalysis of Hydrazone and Oxime Peptide Ligation by Arginine
Ollivier, N.; Agouridas, V.; Snella, B.; Desmet, R.; Drobecq, H.; Vicogne, J.; Melnyk, O. Org Lett 2020, 22, 8608-8612.
DOI : 10.1021/acs.orglett.0c03195
Chemical Protein Synthesis in Medicinal Chemistry
Agouridas, V.; El Mahdi, O.; Melnyk, O. J. Med. Chem. 2020, 63, 15140–15152.
DOI: 10.1021/acs.jmedchem.0c01082